Antitumor antibiotic BMY-42448

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 71, 536 187, 536 23, 536 181, C07H 1700

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active

050829335

ABSTRACT:
A new antibiotic designated BMY-42448 is produced by fermentation of Micromonospora narashinoensis strain C39217-R109-7 (ATCC-53791). BMY-42448 exhibits both in vitro and in vivo antitumor activity.

REFERENCES:
patent: Re32034 (1985-11-01), Chabala
patent: 4550160 (1985-10-01), Mrozik
Tomita, F. et al., J. Antibiot., 33, 668, 940, 946 (1980); Waitz, J. A. et al., J. Antibiotics, 34, 1101 (1981); Mallams, A. K. et al.
J. Am. Chem. Soc. 103, 3938, 3940 (1981); Muntwyler, R. et al. Helv. Chem. Acta, 55, 2071 (1972).

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