Antitumor antibiotic

Details Antitumor antibiotic Antitumor antibiotic

1991-10-22

1994-04-19

Lilling, Herbert J.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

435 711, 435169, 4352521, 435825, C12R 2104, C12R 106, C12P 103

Patent

active

053043731

ABSTRACT:
A certain fermentation product of Actinomadura strain Q473-8 yields, when suitably treated, a novel compound having both antibiotic and antitumor activities.

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patent: 5087567 (1992-02-01), Dabrah et al.
Napier et al, "Neocarzinostatin Chromophore", Biochem. Biophys. Res. Commun., 89, (1979), pp. 635-642.
Suzuki et al, "Auromomycin Chromophore", Biochem. Biophys. Res. Commun., 94, (1980), pp. 255-261.
Otani et al, "Isolation and Characterization of Non-protein Chromophore and its Degradation Product from Antibiotic C-1027", Journal of Antibiotics, 44 (1991), pp. 564-568.

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