Antitumor anthracycline glycosides, intermediates thereof, and c

Details Antitumor anthracycline glycosides, intermediates thereof, and c Antitumor anthracycline glycosides, intermediates thereof, and c

1987-09-28

1989-06-13

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 64, A61K 3170, C07H 1524

Patent

active

048393460

ABSTRACT:
New anthracycline glycosides having formula: ##STR1## wherein R.sup.1 is hydrogen or hydroxy and either R.sup.2 or R.sup.3 is hydrogen with the other amino-methyl are described. The new compounds and their pharmaceutically acceptable addition salts are useful as antitumour agents.

REFERENCES:
patent: 4039663 (1977-08-01), Arcamone et al.
patent: 4562177 (1985-12-01), Horton et al.
patent: 4563444 (1986-01-01), Angelucci et al.
Cram et al., Organic Chemistry, 2nd ed., 1964, p. 526.

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