Antitumor agents albacarcins V and M

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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435886, 424180, C12P 1718, C12R 1465, A01N 3100

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active

044618310

ABSTRACT:
Novel antitumor antibiotics designated herein as albacarcins M and V are produced by fermentation of Streptomyces albaduncas strain C-38291 (ATCC 39151). The new antibiotics possess antibacterial activity and also inhibit the growth of mammalian tumors such as P388 leukemia in mice.

REFERENCES:
patent: 3265588 (1966-08-01), Kawaguchi et al.
patent: 4360595 (1982-11-01), Balitz et al.
Antibiotiki, 27, (7), pp. 507-511, (1982).

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