Antitumor active substance, process for preparing the same, drug

Details Antitumor active substance, process for preparing the same, drug Antitumor active substance, process for preparing the same, drug

1985-12-19

1990-02-06

Hazel, Blondel

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4351723, 435 704, 435 695, 424 852, 530351, C12P 2100, C12N 1500, C07K 1300

Patent

active

048988189

ABSTRACT:
This invention provides an antitumor active substance GIF, a process for preparing the same, an antitumor composition containing the substance, a gene coding for GIF, a vector containing the gene and a recombinant microorganism, the substance GIF comprises as its component protein polypeptide A of the following primary structure. ##STR1## wherein X is Cys or Ser and Z is H or a peptide represented by the amino acid sequence ##STR2## or a peptide having the above sequence wherein at least one amino acid is removed from the N terminal or an amino acid.

REFERENCES:
patent: 4762914 (1988-08-01), Auron et al.
patent: 4766069 (1988-08-01), Auron et al.
J. of Immunol., vol. 122, pp. 2112-2118 (1979).
Fed. Proc., vol. 41, pp. 257-262 (1982).
Cell. Immun., vol. 80, pp. 223-229 (1983).
Nature, vol. 309, pp. 56-59 (1984).
J. Exp. Med., vol. 160, pp. 772-787 (1984).
Cell. Immun., vol. 48, pp. 433-436 (1979).
Biochem. & Biophys. Res. Com., vol. 141, pp. 285-291 (1986).
J. Exp. Med., vol. 161, pp. 490-502 (1985).
J. Exp. Med., vol. 162, pp. 790-801 (1985).
J. Exp. Med., vol. 164, pp. 237-250 (1985).
The J. of Immunol., vol. 135, pp. 3962-3968 (1985).
The J. of Immunol., vol. 136, pp. 2483-2485 (1986).
Cell. Immun., vol. 63, pp. 164-176 (1981).
J. Exp. Med., vol. 150, pp. 709-714 (1979).
The J. of Immunol., vol. 130, pp. 2708-2714 (1983).
The J. of Immunol., vol. 132, pp. 1311-1316 (1984).
Nature, vol. 314, pp. 266-268 (1985).
Nature, vol. 312, pp. 458-462 (1984).
R. of Inf. Diseases, vol. 6, pp. 51-95 (1984).
The N.E. J. of Med., vol. 311, p. 1413 (1984).
Proc. Natl. Acad. Sci. USA, vol. 81, pp. 7907-7911 (1984).
Nature, vol. 315, pp. 641-647 (1985).
Nucleic Acids Res., vol. 13, pp. 5869-5882 (1985).
Nature, vol. 304, pp. 449-451 (1983).
The J. of Immunol., vol. 136, pp. 3098-3102 (1986).
J. Clin. Inv., vol. 79, pp. 48-51 (1987).
6th Intl. Cong. of Immun., pp. 343-346 (1986).
Biochem. & Biophys. Res. Comm., vol. 143, pp. 345-352 (1987).
Eur. J. Immunol., vol. 14, pp. 898-901 (1984).
Bio/Tech, vol. 4, pp. 1078-1082 (1986).
Clin. Exp. Immunol, vol. 55, pp. 295-302 (1984).
Arth. & Rheum., vol. 26, pp. 975-983 (1983).
Arth. & Rheum., vol. 28, pp. 853-862 (1985).
Immunol. Rev., vol. 63, pp. 51-72 (1982).
The J. of Immunol., vol. 136, pp. 2492-2497 (1986).
The J. of Immunol., vol. 136, pp. 3304-3310 (1986).
Immunol. Today, vol. 7, pp. 45-456 (1986).
Jpn. J. Cancer Res. (Gann), vol. 77, pp. 767-773 (1986).
Proc. of AARC, vol. 26, pp. 1058 (1985).
The Physiol., . . . Inteluekin-1, Liss, Alan R., pp. 253-262 (1985).

Affiliated with

Also associated with

Rating

Antitumor active substance, process for preparing the same, drug does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antitumor active substance, process for preparing the same, drug, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antitumor active substance, process for preparing the same, drug will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-441583