Antithrombotic treatment with calix(n)arene compounds

Details Antithrombotic treatment with calix(n)arene compounds Antithrombotic treatment with calix(n)arene compounds

1992-08-06

1995-04-25

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

C-o-group doai

514680, A61K 3105

Patent

active

054099595

ABSTRACT:
A method of inhibiting thrombus formation in a mammalian subject. The method involves administering to the subject a therapeutically effective dose of a calix(n)arene compound derivatized, at its ring positions meta to the bridge attachments to the ring, with polar substituents having terminal sulfonate groups, including esters and amides which are cleavable in vivo.

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