Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 15 to 23 amino acid residues in defined sequence
Patent
1997-12-02
1999-08-03
Tsang, Cecilia J.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
15 to 23 amino acid residues in defined sequence
530327, 530328, 530329, 514 14, 514 15, 514 16, C07K 520
Patent
active
059326930
ABSTRACT:
Novel short peptides are disclosed which are selected from the group consisting of TAVTQTYGGNSNGEP and fragments thereof containing the minimal sequence TAVTQTY. These peptides are antithrombotic agents and mediate divalent cation-independent adhesion of platelets to fibronectin.
REFERENCES:
patent: 4517686 (1985-05-01), Ruoslahti et al.
patent: 4578079 (1986-03-01), Ruoslahti et al.
patent: 4589881 (1986-05-01), Pierschbacher et al.
patent: 4857508 (1989-08-01), Adams et al.
patent: 5120830 (1992-06-01), Santoro
Winters, et al., Chemical Abstracts 119:5674, July 5, 1993.
Kornblitt, et al., Chemical Abstracts 103:15515, Nov. 17, 1985.
Mohri et al., Chemical Abstracts 122: 23611, May 8, 1995.
Winters, et al., Blood, vol. 81, No. 7, 1993; pp. 1778-1786.
Staatz et al., J. Biol. Chem. vol. 266, 1991; pp. 7363-7367.
Hynes, Cell, vol. 69, 1992; pp. 11-25.
Piotrowicz et al., J. Cell Biol., vol. 106, 1988; pp. 1359-1373.
Haverstick et al., Blood, vol. 66, 1985; pp. 946-953.
Santoro Samuel A.
Staatz William D.
Gupta Anism
Meyer Scott J.
Tsang Cecilia J.
Washington University
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