Antithrombotic compound

Details Antithrombotic compound Antithrombotic compound

2006-08-31

2009-08-18

Jiang, Shaojia Anna (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S008100, C536S004100, C536S123000, C536S123100

Reexamination Certificate

active

07576071

ABSTRACT:
The present invention relates compounds of the formula Ain-line-formulae description="In-line Formulae" end="lead"?oligosaccharide-spacer-GpIIb/IIIa antagonist   (A).in-line-formulae description="In-line Formulae" end="tail"?The compounds of the invention have antithrombotic activity and can be used in treating or preventing thrombotic diseases.

REFERENCES:
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patent: 6136794 (2000-10-01), Cook et al.
patent: 6384021 (2002-05-01), Mardigulan
patent: 6486129 (2002-11-01), Tromp et al.
patent: WO01/42262 (2001-06-01), None
Merriam-Webster's Collegiate Dictionary, Tenth Edition, published 1998 by Merriam-Webster, Incorporated, p. 924.
2006 Chemical Abstracts Catalog, published 2006 by Chemical Abstracts Srevice, p. 52.
Adang Anton E P et al., A New Generation of Orally Active Antithrombotics: Comparing Strategies in the GPIlb/Illa, Thrombin and Factor Xa Areas, Drugs of the Future 2000; vol. 25(4); pp. 369-383.
Uzan, A., Antithrombotic Agents, Expert Opinion on Emerging Drugs, Jun. 1998, vol. 3, No. 1, pp. 189-208.

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