Antithrombotic compound

Details Antithrombotic compound Antithrombotic compound

2005-04-05

2005-04-05

Peselev, Elli (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S025000, C536S017400, C536S017500, C536S017600, C536S123100

Reexamination Certificate

active

06875755

ABSTRACT:
The present invention relates to compounds of the formula (I), wherein R is independently SO3−or CH3; the spacer is a flexible spacer of a length of 13-25 atoms; the charge of the pentasaccharide residue is compensated by positively charged counterions; and the total number of sulfate groups in the pentasaccharide residue is 4, 5 or 6; or a pharmaceutically acceptable salt, a prodrug or a solvate thereof. The compounds of the invention have antithrombotic activity and can be used in treating or preventing thrombin-related diseases.

REFERENCES:
patent: 99 25720 (1999-05-01), None
patent: 99 65934 (1999-12-01), None
Buijsman, Rogier C. et al: “Design and synthesis of a novel synthetic NAPAP-pentasaccharide conjugate displaying a dual antithrombotic action” Bioorg. Med. Chem. Lett. (1999), 9(14), 2013-2018.

Affiliated with

Also associated with

Rating

Antithrombotic compound does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antithrombotic compound, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antithrombotic compound will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3414965