Surgery – Instruments – Internal pressure applicator
Patent
1996-01-16
1998-03-03
Buiz, Michael
Surgery
Instruments
Internal pressure applicator
600 3, A61B 1700, A61N 500
Patent
active
057229848
ABSTRACT:
Disclosed is a coating material which has both antithrombogenic properties and contains an embedded radioisotope that makes the coating material radioactive As phosphorous 32 is emerging as the preferred isotope for vascular radioisotope stents, and phosphorylcholine has shown promise as an antithrombogenic stent coating, it is envisioned here to produce a stent with a phosphorylcholine coating with some of the phosphorous in the coating being phosphorous 32 rather than the naturally occurring, non-radioactive element phosphorous 31. In this manner one has a stent which has a single stent coating which is both antithrombogenic and radioactive. The stent could also utilize an inner layer which is both antithrombogenic and radioactive and an outer layer which is only antithrombogenic. A preferred embodiment of the invention is to produce a phosphorylcholine coated stent where some of the phosphate groups contain the radioisotope phosphorous 32.
REFERENCES:
patent: 5059166 (1991-10-01), Fischell et al.
patent: 5302168 (1994-04-01), Hess
Fischell David R.
Fischell Tim A.
Buiz Michael
Iso Stent, Inc.
Lewis William W.
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