Antithrombogenic medical material and method of preparing same

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...

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514 2, 514 56, 514801, 514822, 523112, A61L 1700

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048332003

ABSTRACT:
An antithrombogenic medical material with a remarkable antithrombogenic property and histocompatibility as well as sufficient physical strength, formed by fixing a heparinized collagen to a synthetic polymer material is provided. And a method of preparing an antithrombogenic medical material is provided, wherein a synthetic polymer material is subjected to a coating or impregnating treatment with a collagen-containing solution, followed by heparinization of the collagen, and the heparinized collagen is fixed to the synthetic polymer material. This method allows manufacturing of antithrombogenic medical material with ease.

REFERENCES:
patent: 4175182 (1979-11-01), Schmer
patent: 4690973 (1987-09-01), Noishiki et al.
patent: 4704131 (1987-11-01), Noishiki et al.
Noishiki et al., "A Simple Method to Heparinize Biological Materials", J. of Biomed. Mat. Res., vol. 20, 337-346, (1986).

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