Antithrombin nucleotides and proteins from horn fly

Details Antithrombin nucleotides and proteins from horn fly Antithrombin nucleotides and proteins from horn fly

2005-08-09

2005-08-09

Weber, Jon (Department: 1653)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C530S300000, C530S412000, C435S007100, C435S007200, C435S070100, C435S070400, C435S069100, C424S178100, C514S002600, C514S012200, C514S021800

Reexamination Certificate

active

06927279

ABSTRACT:
Compositions and methods for preventing hematophagous infestation of cattle are provided, directed at isolated proteins with antithrombin activity and nucleotide sequences encoding the proteins. The protein named thrombostasin is isolated from the salivary glands ofHaematobia irritans. The compositions are useful as veterinary vaccines in prevention of blood-feeding in cattle by the infesting horn fly. The proteins of the invention are also useful in treatment of thrombosis.

REFERENCES:
patent: WO 98/21324 (1998-05-01), None
Cupp et al., Journal of Medical Entomology, vol. 34, No. 2, pp. 87-94, 1997.
Byford et al., “A Review of Ectoparasites and Their Effect on Cattle Production,”0J. Anim. Sci, 1992, 70:597-602.
Cappello et al., “Isolation and Characterization of the Tsetse Thrombin Inhibitor: A Potent Antithrombotic Peptide from the Saliva of Glossina Morsitans,”Am. J. Trop. Med. Hyg., 1996, 54(5):475-80.
Cappello et al., ERRATUM,Am. J. Trop. Med. Hyg., 1996, 55(1) 118.
Cupp et al., “Blood-Feeding Strategy of Haematobia Irritans (Diptera: Muscidae),”Journal of Medical Entomology, 1998, 35(4) 591-5.
Harris et al., “Horn Flies and Stable Flies: Feeding Activity,”Annals of the Entomological Society of America, 1974, 67(6):891-894.
Kerlin et al., (1992), “Acquired Immune Response of Cattle Exposed to Buffalo Fly (Haematobia Irritans Exigua),”Veterinary Parasitology, 1992, 43:115-129.
Lewis et al., “Polynucleotide Vaccines In Animals: Enhancing and Modulating Responses,”Vaccine, 1997, 15(8):861-864.
Schwinghammer et al., “Psyciological and Nutritional Response of Beef Steers to Infestations of the Hom Fly (Diptera: Muscidae),”Journal of EconomicEntomology, 1986, 79(4):1010-1014.
Tighe et al., (1998), “Gene Vaccination: Plasmid DNA Is More Than Just A Blueprint,”Immunology Today, 1998, 19(2):89-97.

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