Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1976-06-09
1978-05-02
Danison, Walter C.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
210DIG23, 424101, 424177, A23J 106
Patent
active
040874150
ABSTRACT:
High purity antithrombin III is recovered from a procedure in which the other protein fractions in human blood plasma are recovered for further processing. The protein fractions are recovered sequentially in separate steps: fibrinogen and Factor VIII are recovered as a precipitate; prothrombin complex is recovered on the surface of finely divided tricalcium phosphate; albumin and gamma globulin are recovered in an aqueous supernate; a protein precipitate containing lipids, lipoproteins and other trace protein contaminants is recovered; and antithrombin III is recovered as a precipitated phase. The fibrinogen, Factor VIII, prothrombin complex, albumin, gamma globulin and protein contaminants are all recovered in such a way that they are suitable for further processing.
REFERENCES:
patent: 3631018 (1971-12-01), Shanbrom et al.
patent: 3682881 (1972-08-01), Fekete et al.
patent: 3770631 (1973-11-01), Fekete et al.
patent: 3839314 (1974-10-01), Fekete et al.
patent: 3842061 (1974-10-01), Andersson et al.
patent: 3850903 (1974-11-01), Garcia et al.
patent: 3880989 (1975-04-01), Garcia
patent: 3956259 (1976-05-01), Garcia et al.
Machovich et al., Thrombosis Research, 7, pp. 305-313 (1975).
Wagner et al., "Precipitation of Factor VIII with Aliphatic Amino Acids", The Hemophilias International Symposium (1964) pp. 81-86.
Abilgaard, Chemical Abstracts, vol. 67: 78,954s (1967).
Bick Rodger L.
Fekete Lajos F.
Bick Rodger L.
Danison Walter C.
Fekete Lajos F.
Wilson William L.
LandOfFree
Antithrombin III does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antithrombin III, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antithrombin III will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2157908