Antistasin type serine protease inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 2, 514 24, 530324, 530345, 435 691, 435 692, C07K 1481, A61K 3855, A61K 3857

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active

058613773

ABSTRACT:
The present invention relates to novel inhibitors belonging to the family of antistasin-type serine proteinase inhibitors, to their isolation from the medical leech Hirudo medicinalis, to DNA sequences encoding the novel inhibitors, to variants obtained by recombinant DNA technology or peptide synthesis, pharmaceutical compositions containing the inhibitors, and to their use in diagnosis and therapy.

REFERENCES:
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patent: 4668662 (1987-05-01), Tripier
patent: 4835253 (1989-05-01), Burton
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