Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1990-04-23
1993-02-23
Draper, Garnette D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530324, 530855, 930250, 514822, A61K 3764, C07K 710
Patent
active
051890194
ABSTRACT:
A protein having a molecular weight of about 6,000 daltons which is biologically active in the inhibition of Factor Xa during the blood coagulation cascade, a method for producing the protein, methods for inhibiting blood coagulation using the protein, and suitable pharmaceutical compositions.
REFERENCES:
patent: 4752603 (1988-06-01), Collen et al.
patent: 4832849 (1989-05-01), Cardin
J. of Biological Chemistry "The Amino Acid Sequence of Antistasin" vol. 263 (21): 10162-10167, Jul. 25, 1988.
Law Simon W.
Mark George E.
Palladino Linda O.
Silberklang Melvin
Tung Jwu-Sheng
Caruso Charles M.
Draper Garnette D.
Merck & Co. , Inc.
Ossanna Nina
Parr Richard S.
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