Antistaphylococcous human immunoglobulin and method of preparing

Details Antistaphylococcous human immunoglobulin and method of preparing Antistaphylococcous human immunoglobulin and method of preparing

1975-04-15

1977-05-31

Gotts, Lewis

Drug, bio-affecting and body treating compositions

Lymphokine

260112B, 260112R, A61K 3940

Patent

active

040270106

ABSTRACT:
Antistaphylococcous human immunoglobulin consisting of gamma globulin fraction isolated from the plasma of man immunized with staphylococcous toxoid, containing staphylococcous .alpha.-antitoxin in the titre from 50 to 640 Units per ml and agglutinins against staphylococci in the titre to 1:20480 in a physiological or isotonic solution.
The method for preparing said antistaphyloccus human immunoglobulin consists in that the plasma isolated from the blood of donors immunized with staphylococcus toxoid in the doses of 1, 1 and 2 ml, injected at 7-day intervals, is fractionated with ethyl alcohol at subzero temperatures with subsequent isolation of the gamma globulin fraction, its purification, drying and dissolution in physiological or isotonic solution. This immunoglobulin is useful in treating staphylococcal infections.

REFERENCES:
patent: 2437060 (1948-03-01), Williams et al.

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