Single-crystal – oriented-crystal – and epitaxy growth processes; – Processes of growth from liquid or supercritical state – Having growth from a solution comprising a solvent which is...
Reexamination Certificate
2007-06-11
2010-10-12
Kunemund, Robert M (Department: 1714)
Single-crystal, oriented-crystal, and epitaxy growth processes;
Processes of growth from liquid or supercritical state
Having growth from a solution comprising a solvent which is...
C117S069000, C117S070000
Reexamination Certificate
active
07811381
ABSTRACT:
Antisolvent crystallization systems and methods are provided that employ porous hollow fiber membranes. The porous hollow fiber membrane includes a plurality of porous hollow fibers positioned within a shell, each porous hollow fiber defining a lumen side and shell side. A crystallizing solution is introduced to one side of the hollow fibers and an antisolvent is introduced to the other side of the fibers, in either cocurrent or countercurrent flow. One of the antisolvent and the crystallizing solution permeates in part through the porous hollow fiber membrane to the other side and crystals are formed thereby. Permeation of the antisolvent or the crystallizing solution establishes advantageous radial mixing that facilitates crystal formation of a desired size distribution. Downstream mixing, e.g., a completely stirred tank or a static mixer, may be employed to further improve crystallization operations.
REFERENCES:
patent: 6482438 (2002-11-01), Singh et al.
Korean Patent Application No. 1020020058340 to Jung et al., having Publication date of Nov. 18, 2002 (w/ English Abstract page).
Azoury et al., “Crystallization Processes Using Reverse Osmosis,”Journal of Crystal Growth, 79, 654-657 (1986).
Azoury et al., “Habit Modifiers Of Calcium Oxalate Crystals Precipitated In A Reverse Osmosis System,”Journal of Crystal Growth, 76, 259-262 (1986).
Azoury et al., “Calcium Oxalate Precipitation In A Flow System: An Attempt To Simulate The Early Stages Of Stone Formation In The Renal Tubules,”Journal of Urology, 136(1), 150-153 (1986).
Azoury et al., “Generation Of Supersaturation Using Reverse Osmosis,”Chemical Engineering Research&Design, 65, 342-344 (1987).
Curcio et al., “Membrane Crystallizers,”Industrial&Engineering Chemistry Research, 40, 2679-2684 (2001).
Curcio et al., “Membrane Crystallization Of Macromolecular Solutions,”Desalination, 145, 173-177 (2002).
Curcio et al., “Recovery Of Fumaric Acid By Membrane Crystallization In The Production of L-malic Acid,”Separation and Purification Technology, 33, 63-73 (2003).
Curcio et al., “A New Membrane-Based Crystallization Technique: Tests On Lysozyme,”Journal of Crystal Growth, 247, 166-176 (2003).
Todd et al., “Application Of Osmotic Dewatering To The Controlled Crystallization Of Biological Macromolecules And Organic Compounds,”Journal of Crystal Growth, 110, 283-292 (1991).
Zhiqian et al., “Synthesis Of Nanosized Baso4Particles With A Membrane Reactor: Effects Of Operating Parameters On Particles,”Journal of Membrane Science, 209, 153-161 (2002).
Zarkadas et al., “Solid Hollow Fiber Cooling Crystallization,”Industrial&Engineering Chemistry Research, 43(22), 7163-7180 (2004).
Zarkadas et al., “Cooling Crystallization of Paracetamol in Hollow Fiber Devices,”Industrial and Engineering Chemistry Research, 46, 2928-2935 (2007).
Prasad et al., “Dispersion-Free Solvent Extraction With Microporous Hollow-Fiber Modules,”AIChE Journal, 34(2), 177-188 (1988).
Mahajan et al., “Analysis Of Size Distribution And Growth Kinetics During The Batch Crystallization Of L-Asparagine,”AIChE Symposium Series, 87(284), 143-157 (1991).
Deshpande et al., “Effect Of Mixing On Size Distribution During Precipitation Of L-Asparagine In An Agitated Crystallizer,”Proceedings of the 14th International Symposium on Industrial Crystallization, Cambridge, UK, 340-348 (1999).
Garside et al., “Mixing, Reaction And Precipitation: Limits Of Micromixing In An MSMPR Crystallizer,”Chemical Engineering Science, 40(8), 1485-1493 (1985).
Tavare,“Micromixing Limits In An MSMPR Crystallizer,”Chemical Engineering Technology, 12, 1-12 (1989).
Mahajan et al., “Rapid Precipitation Of Biochemicals,”Journal of Physics: Applied Physics, 26(8B), B176-B180 (1993).
Mahajan et al., “Nucleation And Growth Kinetics Of Biochemicals Measured At Very High Supersaturation,”Journal of Crystal Growth, 144(3-4), 281-290 (1993).
Sirkar Kamalesh K.
Zarkadas Dimitrios
Kunemund Robert M
McCarter & English LLP
LandOfFree
Antisolvent crystallization in porous hollow fiber devices... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antisolvent crystallization in porous hollow fiber devices..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antisolvent crystallization in porous hollow fiber devices... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4236971