Antiseptic composition for topical application to the skin

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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424284, 424319, 424344, A61K 3156, A61K 31355, A61K 31195, A61K 3107

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active

042243190

ABSTRACT:
An antiseptic composition, particularly useful against bromidrosis, is prepared by using a disinfecting surface-active amino acid in water having dispersed therein one or several triglycerides of fatty acids of C.sub.12 to C.sub.20. The composition contains 0.3 to 5% by weight of the above bactericidal and fungicidal surface-active amino acid, a fatty material comprising said triglyceride, water and at least one of the vitamins A and E, and preferably also some sterols. The amino acid has the structure RNH(R.sup.1 NH).sub.n R.sup.2 COOH where R is an aliphatic chain of 8 to 18C, R.sup.1 and R.sup.2 are C.sub.1 to C.sub.3 alkylenes, while n is 0 or 1.0 or 2.0. Preferably the composition further contains a pesticide quaternary ammonium derivative.
The composition is very effective agaist bromidrosis, particularly that of the feet, without any irritant action on the skin.

REFERENCES:
patent: 2684946 (1954-07-01), Schmitz
patent: 2700683 (1955-01-01), Tesoro
patent: 2717850 (1955-09-01), Schmitz
patent: 2865859 (1958-12-01), Lubowe
patent: 2942008 (1960-06-01), Lubowe
patent: 2968628 (1961-01-01), Reed
patent: 3039917 (1962-06-01), Schmitz
patent: 3574850 (1971-04-01), Guillon
The Merck Index--8th Ed.--Merck & Co. Inc., (1968), p. 396.

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