Antisense viruses and antisense-ribozyme viruses

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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4352351, 435236, 4353201, 435456, 536 231, 536 2372, 536 245, C12N 1564, C12N 701, C07H 2104, C07H 2102

Patent

active

061070629

ABSTRACT:
Antisense viruses and antisense ribozyme viruses are disclosed. The novel artificial viruses, their synthesis and their use in preventing and treating viral infections are presented.

REFERENCES:
Rhodes et al. "Inhibition of Human Immunodeficiency Virus Replication in Cell Culture by Endogenously Synthesized Antisense RNA", J. Gen. Virol., vol. 71, 1990, pp. 1965-1974.
von Ruden et al. "Inhibition of Human T-Cell Leukemia Virus Type I Replication in Primary Human T Cells That Express Antisense RNA", J. Virol., Feb. 1989, pp. 677-682.
Lima et al. "Implication of RNA Structure on Antisense Oligonucleotide Hybridization Kinetics", Biochemistry, vol. 31, 1992, pp. 12055-12061.

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