Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2005-04-05
2005-04-05
McGarry, Sean (Department: 1635)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C435S375000, C435S377000, C536S023100, C536S024100, C536S024500
Reexamination Certificate
active
06875747
ABSTRACT:
A method of treating polycystic kidney disease by administering an oligonucleotide antisense to c-myc is described. The antisense oligonucleotide is preferably a morpholino oligonucleotide.
REFERENCES:
patent: 6005094 (1999-12-01), Simon et al.
patent: WO 9109033 (1991-06-01), None
patent: WO 9323057 (1993-11-01), None
Oberbauer et al., Kidney Blood Press Res 1996; 19:221-224.*
Cowley et al., Proc. Natl. Acad. Sci. USA, vol. 84, pp. 8394-8398, Dec. 1987.*
Lanoix et al., Oncogene (1996) 13, 1153-1160.*
Koul et al., Kidney International, vol. 50 (1996), pp. 1525-1530.*
Rojanasakul, Advanced Drug Delivery Reviews v. 18, 115-131 (1996).*
Summerton, J. and Weller, D., “Morpholino Antisense Oligomers: Design, Preparation, and Properties”Antisense&Nucleic Acid Drug Development 7:187-189 (1997).
Trudel, M., et al., “C-MYC-induced Apoptosis in Polycystic Kidney Disease Is Bcl-2 and p53 Independent”J. Exp. Med. 186(11):1873-1884 (1997).
Trudel, M., et al., “Polycystic Kidney Disease in SBM Transgenic Mice”American Journal of Pathology 152(1):219-229 (1998).
Gattone, II Vincent H.
Iversen Patrick L.
Mata John E.
AVI Bio Pharma, Inc.
Gorthey LeeAnn
Hui Karen Y.
Judge Linda R.
McGarry Sean
LandOfFree
Antisense to c-myc for treatment of polycystic kidney disease does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antisense to c-myc for treatment of polycystic kidney disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antisense to c-myc for treatment of polycystic kidney disease will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3406556