Antisense strategy for the production of species specific viral

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus

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4351723, 4353201, 514 44, 536 231, 536 245, A01N 6300, C12N 701, C12N 1579, C12N 1586

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059253460

ABSTRACT:
A novel type of insect control agent and methods for controlling insect pests are described. The agent consists of a vector, such as a baculovirus of the polyhedral inclusion body type, containing in an antisense orientation cDNA sequence which has been derived from the complete sense sequence of a gene which is essential for the growth and development of the host from which the sequence is derived. In order for the insect control agent to exert its effect the insect pests which are to be controlled must be susceptible to the vector. Specifically described are the sequences from Choristoneura fumiferana and the human c-myc gene as well the methods of production and use of these agents.

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