Antisense oligonucleotides which reduce expression of the FGFRI

Details Antisense oligonucleotides which reduce expression of the FGFRI Antisense oligonucleotides which reduce expression of the FGFRI

1995-01-10

1998-07-21

Chambers, Jasemine C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 231, 514 44, 4351723, C07H 2104, C07H 2102, C12N 1500

Patent

active

057836833

ABSTRACT:
Antisense molecules, compositions thereof, and vectors encoding antisense RNA, and methods of using antisense molecules, compositions, and vectors for treating human glioblastoma cells in order to suppress the growth of the cells. The antisense molecules are substantially complementary to human fibroblast growth factor receptor gene one (the FGFR1).

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Morishita et al., J. Cell. Biochem, Supp. 0, 17 part E, 1993, 239.
Noble et al., J. Cell. Biochem, Supp. 0, 17 part E, 1993, 219.
Morrison, J. Biol. Chem., 266(2), 1991, 728-734.

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