Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1997-11-20
1999-09-07
LeGuyader, John L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 231, 536 243, 536 2431, 435 6, 435 911, 435375, C07H 2104, C12Q 168
Patent
active
059489022
ABSTRACT:
Oligonucleotides are provided which are targeted to nucleic acids encoding human serine/threonine protein phosphatases and which are capable of inhibiting protein phosphatase expression. Methods of inhibiting the expression of human protein serine/threonine phosphatases using oligonucleotides of the invention are also provided. The present invention further comprises methods of preventing or inhibiting hyperproliferation of cells and methods of treating abnormal conditions, including cancer, using oligonucleotides of the invention.
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Dean Nicholas M.
Honkanen Richard E.
ISIS Pharmaceuticals Inc.
LeGuyader John L.
Shibuya Mark L.
South Alabama Medical Science Foundation
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