Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2006-04-18
2006-04-18
McGarry, Sean (Department: 1635)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S024100, C536S023100, C514S04400A, C435S320100
Reexamination Certificate
active
07030236
ABSTRACT:
The invention relates to treatment of cancers and cancerous cells which over-express α folate receptor (FRα) compared to the normal cells of the same tissue. The invention is directed to antisense oligonucleotides which are complimentary to the coding region of FRα, as well as the pharmaceutical compositions made thereof, and the methods of using the same for treatment of cancers, e.g. cancers of ovary, cervix, uterus, and brain.
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Hansen et al., Teratology vol. 59(6):385, Jun. 1999.
Jhaveri et al., Proceedings of the American Association for Cancer Research Annual Meeting, No. 41, p. 643, Mar. 2000.
Xin-Lau et al The Journal of Biological Chemistry, vol. 271(41):25539-25547, 1996.
Chung Koong-Nah
Elwood Patrick Clay
Jhaveri Mona Savitri
Fleshner & Kim LLP
McGarry Sean
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