Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1990-02-26
1993-09-28
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
536 245, A61K 3170, C07H 2100, C07H 2102, C07H 2104
Patent
active
052486702
ABSTRACT:
Antisense oligonucleotides are disclosed having a length of 15-30 nucleotides containing the CAT sequence and hybridizable to herpes simplex virus type I gene UL13, UL39, or UL40. These antisense oligomers inhibit the replication of the virus at least three-fold. Pharmaceutical compositions containing these oligonucleotides as the active ingredients are also disclosed.
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Crooke Stanley T.
Draper Kenneth G.
Ecker David J.
Mirabelli Christopher K.
Brown Johnnie R.
ISIS Pharmaceuticals Inc.
Kunz Gary L.
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