Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1997-03-04
1998-11-03
LeGuyader, John L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 6, 4351721, 435375, 536 231, 536 241, 536 243, 514 44, C07H 2102, C07H 2104, C12Q 168
Patent
active
058310690
ABSTRACT:
The present invention provides an oligonucleotide having the nucleotide sequence complementary to the respiratory synctial virus nucleotide sequencenumber 98-116 of the respiratory synctial virus antigenome or nucleotide sequence number 627-645 of the respiratory synctial virus antigenome. Also provided is a composition comprising an oligonucleotide according the present invention and a physiologically acceptable carrier therefore. Also provided are various methods of using these novel oligonucleotides.
REFERENCES:
Branch, A. A Good Antisense is Hard to Find. TIBS vol. 23 :45-50, Feb. 1998.
Jairath, S., et al. Inhibition of Respiratory Syncytial Replication by Antisense Oligodeoxyribonucleotides. Antiviral Research vol. 33:201-213, Feb. 1997.
Adler Benjamin Aaron
LeGuyader John L.
McGarry Sean
South Alabama Medical Science Foundation
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