Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of regulating cell metabolism or physiology
Patent
1999-07-21
2000-10-10
Elliott, George C.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Method of regulating cell metabolism or physiology
435 6, 435 911, 435366, 536 231, 536 2431, 536 2433, 536245, C07H 2104, C12Q 168, C12N 1585
Patent
active
061300888
ABSTRACT:
Antisense compounds, compositions and methods are provided for modulating the expression of Telomeric Repeat Binding Factor 1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Telomeric Repeat Binding Factor 1. Methods of using these compounds for modulation of Telomeric Repeat Binding Factor 1 expression and for treatment of diseases associated with expression of Telomeric Repeat Binding Factor 1 are provided.
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Cowsert Lex M.
Monia Brett P.
Elliott George C.
Isis Pharmaceuticals , Inc.
Schmidt Mary Melissa
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