Antisense modulation of Jun N-terminal kinase kinase-1 expressio

Details Antisense modulation of Jun N-terminal kinase kinase-1 expressio Antisense modulation of Jun N-terminal kinase kinase-1 expressio

1999-07-21

2000-01-04

Brusca, John S.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Method of regulating cell metabolism or physiology

435 6, 435 911, 435 913, 536 231, 536 241, 536 245, C07H 2104, C12Q 168, C12N 1500

Patent

active

060109068

ABSTRACT:
Antisense compounds, compositions and methods are provided for modulating the expression of Jun N-terminal Kinase Kinase-1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Jun N-terminal Kinase Kinase-1. Methods of using these compounds for modulation of Jun N-terminal Kinase Kinase-1 expression and for treatment of diseases associated with expression of Jun N-terminal Kinase Kinase-1 are provided.

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