Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1998-11-20
1999-11-02
Degen, Nancy
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 231, 536 2433, 536 243, 514 44, 435 6, 435375, 435440, 435 911, C12P 1934, A61K 4800, C07H 2104, C07H 2102
Patent
active
059773413
ABSTRACT:
Antisense compounds, compositions and methods are provided for modulating the expression of Inhibitor-kappa B Kinase-beta. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Inhibitor-kappa B Kinase-beta. Methods of using these compounds for modulation of Inhibitor-kappa B Kinase-beta expression and for treatment of diseases associated with expression of Inhibitor-kappa B Kinase-beta are provided.
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Cowsert Lex M.
Monia Brett P.
Degen Nancy
Epps Janet L.
Isis Pharmaceuticals , Inc.
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