Antisense inhibition of MAP kinase kinase 6 expression

Details Antisense inhibition of MAP kinase kinase 6 expression Antisense inhibition of MAP kinase kinase 6 expression

1999-07-19

2000-03-07

LeGuyader, John L.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Method of regulating cell metabolism or physiology

435 6, 435 911, 435325, 435366, 536 231, 536 2431, 536 2433, 536 245, C07H 2104, C12N 1500, C12Q 168

Patent

active

060339101

ABSTRACT:
Antisense compounds, compositions and methods are provided for modulating the expression of MAP kinase kinase 6. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding MAP kinase kinase 6. Methods of using these compounds for modulation of MAP kinase kinase 6 expression and for treatment of diseases associated with expression of MAP kinase kinase 6 are provided.

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