Antisecretory heterocyclic amidine compounds

Details Antisecretory heterocyclic amidine compounds Antisecretory heterocyclic amidine compounds

1978-08-16

1981-02-24

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Bacterium or component thereof or substance produced by said...

546278, 546300, 546330, 546332, 548205, 548342, 424275, 549 61, 549 65, 549 68, 549 75, 549 76, 549 77, 2603472, 2603473, 2603477, 2603478, 544212, 546256, 546262, 546276, 546277, A61K 3134, A61K 3138, C07D30754, C07D33324

Patent

active

042528194

ABSTRACT:
Novel heterocyclic compounds shown by the formula ##STR1## wherein Het represents a 5-membered or 6-membered heterocyclic group which may have substituent(s); Z represents a sulfur atom or oxygen atom; X represents an oxygen atom or the unsubstituted or substituted imino group shown by N--R.sub.1 (wherein R.sub.1 is a hydrogen atom, a lower alkyl group, a cyano group, an unsubstituted or alkyl substituted carbamoyl group, an unsubstituted or lower alkyl substituted thiocarbamoyl group, or a lower alkanoylamino group); Y represents a hydrogen atom, a lower alkyl group which may have substituent(s), a cycloalkyl group of 3-6 carbon atoms, a lower alkenyl group, a lower alkynyl group, an aryl group which may have substituent(s), an aralkyl group which may have substituent(s), a hydroxyl group, a cyano group, a carbamoyl group, an amidino group, an alkanoyl group which may have been substituted by halogen atom(s),

REFERENCES:
patent: 3347874 (1967-10-01), Elog et al.
patent: 3476768 (1969-11-01), McFarland
patent: 3742050 (1973-06-01), Hodson
patent: 3816457 (1974-06-01), Grisar et al.
patent: 3987158 (1976-10-01), Hodson
patent: 4128658 (1978-12-01), Price et al.
patent: 4203909 (1980-05-01), Algieri et al.

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