Antipsychotic chroman derivatives of benzodioxanmethylamine

Details Antipsychotic chroman derivatives of benzodioxanmethylamine Antipsychotic chroman derivatives of benzodioxanmethylamine

1992-09-03

1993-09-14

Cintins, Marianne M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549366, C07D31142

Patent

active

052450511

ABSTRACT:
A compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are, independently, hydrogen, alkyl, alkoxy, aralkoxy, alkanoyloxy, hydroxy, halo, amino, mono- or dialkylamino, alkanamido or sulfonamido, or R.sup.1 and R.sup.2 together are methylenedioxy, ethylenedioxy, or propylenedioxy; R.sup.3 is hydrogen or alkyl; n is one of the integers 2,3 or 4; X is --C(.dbd.O)-- or --(CH.sub.2).sub.m --, in which m is the integer 0 or 1; Y is methylene, ethylene or ethenylene, or a pharmaceutically acceptable salt thereof, are antipsychotic agents.

REFERENCES:
patent: 4704390 (1987-11-01), Caprathe et al.
Chemical Abstracts Service CA100:191886j 1982.
Fozard et al., Br. J. Pharmacol. 90, 273P (1987).

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