Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1977-07-28
1979-04-10
Trousof, Natalie
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
2603265S, 2603265SF, 2603265B, 2602444, A61K 31445, C07D40104, C07D40114
Patent
active
041489039
ABSTRACT:
Pyrrolo[2,1-b][3]benzazepines with a piperidinylidene group in the 11-position have utility as antipsychotic agents. They also demonstrate antiserotonin and antihistaminic activity. They are prepared by reaction of a pyrrolo[2,1-b][3]benzazepin-11-one with a piperidinyl magnesium halide followed by dehydration.
REFERENCES:
patent: 3014911 (1961-12-01), Engelhardt
patent: 3458522 (1969-07-01), Galantay
patent: 4031222 (1977-06-01), Remy
patent: 4056536 (1977-11-01), Atkinson et al.
Gordon, M. Psychopharmacological Agents, vol. I, Academic Press, New York, 1964, p. 600.
Atkinson Joseph G.
Belanger Patrice C.
Remy David C.
Rooney Clarence S.
Merck & Co. , Inc.
Nicholson William H.
Schwartz Richard A.
Trousof Natalie
Westlake, Jr. Harry E.
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