Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-06-18
1993-11-30
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514306, 514314, 514317, 514318, 514323, 514326, 514415, 514419, 544335, 546146, 546174, 546176, 546192, 546201, 546225, 546236, 546276, 546194, 546246, 546247, 546248, 548254, A61K 31505, C07D23926
Patent
active
052665720
ABSTRACT:
There are provided cycloalkyl piperidine compounds which are useful in the treatment of physiological or drug-induced psychosis or dyskinesia in a mammal. These novel compounds are selective sigma receptor antagonists and have a low potential for movement disorder side effects associated with typical antipsychotic agents.
REFERENCES:
patent: 4294841 (1981-10-01), Champseix et al.
Irwin et al, J. Med. Chemistry, vol. 15 (6), pp. 690-692, 1972.
Eistetter et al, CA95: 24830h, 1981.
Tryzellaar et al, CA96: 123074s, 1982.
Cain Gary A.
Gilligan Paul J.
Tam Sang W.
Ferguson Blair Q.
Horn Margaret A.
Ivy C. Warren
The Du Pont Merck Pharmaceutical Company
Trinh Ba K.
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