Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1992-02-06
1993-09-07
Ivy, C. Warren
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
546146, 546174, 546176, 546192, 546225, 546236, 546276, 546256, 548254, C07D23926, C07D23932
Patent
active
052430480
ABSTRACT:
There are provided cycloalkyl piperidine compounds which are useful in the treatment of physiological or drug-induced psychosis or dyskinesia in a mammal. These novel compounds are selective sigma receptor antagonists and have a low potential for movement disorder side effects associated with typical antipsychotic agents.
REFERENCES:
patent: 4294841 (1981-10-01), Champsiex et al.
Irwin et al., J. Med. Chem., 15(6), pp. 690-691, 1972.
Cain Gary A.
Gilligan Paul J.
Tam Sang W.
Ferguson Blair Q.
Horn Margaret
Ivy C. Warren
The Du Pont Merck Pharmaceutical Company
Trinh Ba K.
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