Antipsychotic 1-[4,4-Bis(4-fluorophenyl) butyl]-4-phenoxy-1,2,3,

Details Antipsychotic 1-[4,4-Bis(4-fluorophenyl) butyl]-4-phenoxy-1,2,3, Antipsychotic 1-[4,4-Bis(4-fluorophenyl) butyl]-4-phenoxy-1,2,3,

1977-09-26

1979-01-16

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

26029375, 26029379, 26029383, 2602949, 260296AE, 260297R, 424267, A61K 3144, C07D21174, C07D21369

Patent

active

041349822

ABSTRACT:
1-[4,4-Bis(4-fluorophenyl)butyl]-4-phenoxy-1,2,3,6-tetrahydropyridines and related piperidines are disclosed in the present invention. These compounds have the structural formulas: ##STR1## in which X is hydrogen, halogen, dihalogen, trifluoromethyl, lower alkoxy, nitro, amino, cyano, lower alkyl, aryl or substituted aryl. Also included are the corresponding non-toxic, pharmaceutically acceptable acid addition salts, and the N-oxides of compounds of the formulas I and II.
The above compounds are useful in the management of manifestations of psychotic disorders.

REFERENCES:
patent: 3260723 (1966-07-01), L'Italien
patent: 3927006 (1975-12-01), Edenhofer

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