Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-11-14
1991-12-24
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514863, 549292, A61K 3135, C07D30930
Patent
active
050753274
ABSTRACT:
A compound and process of making thereof of formula ##STR1## wherein R.sub.1 is hydrogen; and A is alkyl; cycloalkyl; alkenyl; alkyl substituted with trifluoromethyl; phenyl; halophenyl; phenyl-C.sub.1-3 alkyl; phenyl-C.sub.1-3 alkyl substituted on the phenyl with 1 to 3 substituents selected from the group consisting of halo, C.sub.1-3 alkyl, and C.sub.1-3 alkoxy; or
REFERENCES:
patent: 4231938 (1980-11-01), Monaghan et al.
patent: 4293496 (1981-10-01), Willard
patent: 4294926 (1981-10-01), Monaghan et al.
patent: 4346227 (1982-08-01), Terahara et al.
patent: 4444784 (1984-04-01), Hoffman et al.
patent: 4450171 (1984-05-01), Hoffman et al.
patent: 4582915 (1986-04-01), Sleteinger et al.
patent: 4611067 (1986-09-01), Valente et al.
patent: 4668699 (1987-05-01), Hoffman et al.
patent: 4766145 (1988-08-01), Lee et al.
patent: 4771071 (1988-09-01), Hoffman et al.
patent: 4795811 (1989-01-01), Graham et al.
Ponec et al., "Differentiation of Human Keratinocytes: Changes in Lipid Synthesis, Plasma Membrane Lipid Composition and .sup.125 1-EGF Binding Upon Administration of 25-Hydroxy Cholesterol and Meloinolin" J. Cellular Physiology, 133:358-364, (1987).
J. Antibiot. 36(5), 604 (1983).
J. Antibiot. 36(5), 608 (1983).
J. Antibiot., 36(7), 918 (1983).
J. Med. Chem., 28(4) 401 (1985).
J. Antibiot., 38(5), 605 (1985).
Chemical Abstract 102:7864 3F (1985).
Page 96 of the Chemical and Engineering News, Aug. 1, 1988.
Chem. Abstract 180 "Total Synthesis of the Angular Methyl Regioisomer of Compactin".
Drugs of Future, vol. 13, No. 5, 1988, p. 475.
Clin. Pharm., 7/1, 21-36 (1988).
J. Cell Physiol., 133/2, 358-364 (1987).
Fitzpatrick, T. B. et al., Dermatology in General Medicine, 3rd Ed., Chapter 5, pp. 49-50 and 154-159 (1987).
Tang Peng C.
Uskokovic Milan R.
Gould George M.
Hoffmann-La Roche Inc.
Ivy C. Warren
Johnston George W.
Kass Alan P.
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