Antiprotozoal cyclic tetrapeptides

Details Antiprotozoal cyclic tetrapeptides Antiprotozoal cyclic tetrapeptides

1997-01-27

1999-07-13

Huff, Sheela

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Cyclic peptides

530318, C07K 500

Patent

active

059228377

ABSTRACT:
The present invention provides novel cyclic tetrapeptides useful in the treatment or prevention of protozoal diseases; in particular, the novel compounds are active against the causative pathogens in malaria, toxoplasmosis, and coccidiosis. The invention also relates to the use of known compounds which are histone deacetylase inhibitors as antiprotozoal agents.

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