Antiprotozoal compounds

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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260396R, A01N 924, C07C 5012

Patent

active

044851162

ABSTRACT:
1,4-Naphthoquinones of formula (I), methods for their preparation, veterinary formulations thereof, and the use thereof in animal therapy are disclosed. ##STR1## Particularly preferred compounds of formula (I) are, 2-[trans-(4-t-butylcyclohexyl)methyl]-3-hydroxy-1,4-naphthoquinone, and 2-[trans-(4-t-pentyl cyclohexyl)methyl]3-hydroxy-1,4-naphthoquinone. The compounds are of value as anti-protozoal agents, in particular as anti-theilerial agents.

REFERENCES:
patent: 2553647 (1951-05-01), Fieser
patent: 3347742 (1967-10-01), Rogers
patent: 3393211 (1968-07-01), Fisher et al.
patent: 3578686 (1971-05-01), Tullar et al.
patent: 3682991 (1972-08-01), Tullar et al.
patent: 4110473 (1978-08-01), Fugitt et al.

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