Antiprotozoal composition containing a 2-nitroimidazole derivati

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 3104

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active

053107497

ABSTRACT:
Disclosed herein is an antiprotozoal composition containing a 2-nitroimidazole derivative as its active component. This drug is especially useful against Trypanosoma cruzi. Process for the preparation is also disclosed.

REFERENCES:
patent: 4241060 (1980-12-01), Smithen
patent: 4515790 (1985-05-01), Hofheinz
Patent Abstracts of Japan, 2-Nitromidazole Derivative and its, Preparation, vol. 8, (JP-A-59 139 363), 1984.
K. Sasai et al, Int. J. Radiat. Biol, 1990, vol. 57, No. 5, pp. 971-980.

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