Antiproliferative activity of the leiodermatolide class of...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S450000

Reexamination Certificate

active

07626043

ABSTRACT:
The subject invention provides novel biologically active compounds that have utility for use in inhibiting cellular proliferation. Pharmaceutical compositions comprising these compounds are also provided. In a specific embodiment, the compounds and compositions of the subject invention can be used in the treatment of cancer.

REFERENCES:
patent: 5430053 (1995-07-01), Pettit et al.
Gunasekera, S. P. et al., “Discodermolide: A New Bioactive Polyhydroxylated Lactone from the Marine SpongeDiscodermia dissoluta,” Journal of Organic Chemistry, 1990, Vol. 55, No. 16, pp. 4912-4915.
Pisera, A. et al., “Family Azoricidae Sollas, 1888,”Systema Porifera: A Guide to the Classification of Sponges, 2002, pp. 352-355.
Van Soest, R. W. M. et al., “Barbados Deep-Water Sponges,”Studies on the Fauna of Curaçao and Other Caribbean Islands: No. 215, 1988, pp. 1-175.

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