Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing
Patent
1987-10-08
1988-07-26
Brown, J. R.
Drug, bio-affecting and body treating compositions
Dentifrices
Fluorine or fluorine compound containing
514901, 424 57, A61K 718
Patent
active
047599251
ABSTRACT:
The perfluoroalkyl surfactant (PAS) of the general formula C.sub.x F.sub.2x+1 (CH.sub.2).sub.n S(CH.sub.2).sub.n,CO.sub.2 M wherein x is an integer of 3-8, each of n and n' is an interger of 2-4 and may be the same or different and M is hydrogen, an alkali metal or ammonium, provides an oral composition, such as a dentifrice or a mouthwash with effect in prevent plaque formation. A preferred PAS is Zonyl FSA, C.sub.3-8 F.sub.7-17 (CH.sub.2).sub.2 S(CH.sub.2).sub.2 COOLi.
REFERENCES:
patent: 2829086 (1958-04-01), Kirschenbauer
Chemical Abstracts, vol. 90, No. 2, Jan. 8, 1979, p. 117, Abst. No. 123623w, "Method and Composition for Removing Calcium Sulfate Scale Deposits from Surfaces".
Gaffar, J. of Pharmaceutical Science, vol. 74, No. 11, Nov. 1985.
Esposito Anthony
Gaffar Abdul
Brown J. R.
Colgate-Palmolive Company
Grill Murray M.
Moezie F. T.
Stone Robert L.
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