Antiplaque oral composition containing perfluoroalkyl sulfate su

Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing

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514901, 424 57, A61K 718

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active

047599251

ABSTRACT:
The perfluoroalkyl surfactant (PAS) of the general formula C.sub.x F.sub.2x+1 (CH.sub.2).sub.n S(CH.sub.2).sub.n,CO.sub.2 M wherein x is an integer of 3-8, each of n and n' is an interger of 2-4 and may be the same or different and M is hydrogen, an alkali metal or ammonium, provides an oral composition, such as a dentifrice or a mouthwash with effect in prevent plaque formation. A preferred PAS is Zonyl FSA, C.sub.3-8 F.sub.7-17 (CH.sub.2).sub.2 S(CH.sub.2).sub.2 COOLi.

REFERENCES:
patent: 2829086 (1958-04-01), Kirschenbauer
Chemical Abstracts, vol. 90, No. 2, Jan. 8, 1979, p. 117, Abst. No. 123623w, "Method and Composition for Removing Calcium Sulfate Scale Deposits from Surfaces".
Gaffar, J. of Pharmaceutical Science, vol. 74, No. 11, Nov. 1985.

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