Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – C-o-group doai
Patent
1996-05-17
1998-03-03
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
C-o-group doai
514734, 514731, 424 49, A01N 3108, A61K 3105
Patent
active
057235007
ABSTRACT:
An oral antiplaque composition and treatment of teeth therewith wherein the essential antiplaque agent is a substantially water insoluble noncationic antibacterial phenol containing, relative to the hydroxyl group, an alkyl or cycloalkyl group, preferably tert.-butyl (t-butyl), in 2-position, and substituents in one or both of the 4- and 5-positions, one of which may be phenyl or 2', 3' and/or 4' substituted alkyl or cycloalkyl phenyl, preferably 4'-t-butyl phenyl or a phenanthrene containing a hydroxyl substituent in the 2- or 3-position and alkyl or cycloalkyl, preferably t-butyl, substituents in the other of the 2- and 3-positions and in at least one of the other rings. Novel antibacterial alkylated phenols are also described.
REFERENCES:
patent: 3800051 (1974-03-01), Barnhart et al.
patent: 4321257 (1982-03-01), Sipos
patent: 5188821 (1993-02-01), Gaffar et al.
patent: 5487893 (1996-01-01), Vachy
Chemical Abstracts vol. 93, No. 17, Oct. 27, 1980.
(Abstract No. 162715--Japan Kokai 55 016 802--Ajinomoto).
Brahms John C.
Kelly Ernest E.
Stringer Orum D.
Subramanian Malathy
Cintins Marianne M.
Colgate-Palmolive Company
Goldfine Henry S.
Jones Dwayne C.
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