Antipicornaviral compounds and methods for their use and prepara

Details Antipicornaviral compounds and methods for their use and prepara Antipicornaviral compounds and methods for their use and prepara

1997-05-02

1999-01-05

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549483, 549488, 560122, 560128, 560 27, C07D30712, C07D30710, C07C 6974, C07C 69757

Patent

active

058565302

ABSTRACT:
Picornaviral 3C protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of picornaviral 3C proteases. These compounds, as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses. Several novel methods and intermediates can be used to prepare the novel picornaviral 3C protease inhibitors of the present invention.

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