Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Heavy metal or compound thereof
Patent
1994-06-01
1996-12-31
Dodson, Shelley A.
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Heavy metal or compound thereof
25218233, 25218235, 423608, 423625, 424 65, 424 66, 424 68, 424600, A61K 3324, A61K 732, C01G 2500, C01F 700
Patent
active
055891969
ABSTRACT:
A composition of zirconyl hydroxy chloride and aluminum chlorhydroxide in stable solid form having improved antiperspirant efficacy when dissolved in water is made by heating a 2-20% by weight aqueous solution containing at least the aluminum chlorhydroxide component of the composition at a temperature of at least 50.degree. C. until the ratio of the height of peak 4 at Kd=0.7 to that of peak 3 at Kd=0.5 as measured by gel permeation chromatography on cross-linked dextran is at least 2:1, then subjecting the solution to rapid drying to solid form.
REFERENCES:
patent: 2854382 (1958-09-01), Grad
patent: 2906668 (1959-09-01), Beekman
patent: 4359456 (1982-11-01), Gosling
patent: 4435382 (1984-03-01), Shin
Callaghan David T.
Phipps Alan M.
Provancal Stephen J.
Dodson Shelley A.
The Gillette Company
Williams Stephan P.
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