Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1998-01-16
1999-03-16
Stockton, Laura L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514450, 536 71, 549264, A61K 3170, C07H 1708, A01N 4390
Patent
active
058830804
ABSTRACT:
Antiparasitic avermectin derivatives of formula (I), where the broken line represents an optional bond, R.sup.1 and R.sup.4 are independently H, OH, halo, oximino, or an organic radical, R.sup.2, R.sup.6 and R.sup.7 are organic radicals and R.sup.3 is alpha-oleandrosyl or 4'-(alpha-oleandrosyl)-alpha-oleandrosyl optionally substituted at the 4'- or 4"-position, and R.sup.12 and R.sup.13 are independently H, CN, CONH.sub.2, C.sub.1 -C.sub.8 alkyl or aryl optionally substituted with at least one halo, OH, C.sub.1 -C.sub.8 alkylthio group.
REFERENCES:
patent: 5411946 (1995-05-01), Newbold et al.
patent: 5516761 (1996-05-01), Choi et al.
Andrew Streifwieser, Jr. and Clayton H. Heathcock, "Introduction to Organic Chemistry", 3rd Edition, Macmillan Publishing Company, New York, 1985, pp. 396-398.
Dutton Christopher James
Gibson Stephen Paul
Witty Michael John
Benson Gregg C.
Pfizer Inc.
Richardson Peter C.
Ronau Robert T.
Stockton Laura L.
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