Antiparasitic marcfortines and paraherquamides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544341, A61K 3150, A61K 31495, C07D24136

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active

057030782

ABSTRACT:
The present invention includes various substituted marcfortines of the type exemplfied by the compounds of formula ##STR1## and paraherquamides which are useful as antiparasitic agents.

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Blanchflower, S. E. et al., J. Antibiot. (1993), 46(9), 1355-63, 1993.
CA:vol. 118, No. 19, (1993) 192076d.
Polonsky, J., et al., J. Chem. Soc. Chem. Comm., pp. 601-602 (1980).
Prange, T., et al., Tetrahedron Letters, 22, pp. 1977-1980 (1981).
Yamazaki, M., et al., Tetrahedron Letters, 22, pp. 135-136 (1981).
Liesch, J. M., et al., J. Antib., 43, pp. 1380-1386 (1990).
Blanchflower, S. E., et al., J. Antib., 44, pp. 492-497 (1991).

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