Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Synthetic or structurally-modified peptidoglycan or...
Patent
1981-12-07
1983-06-28
Fan, Jane T.
Drug, bio-affecting and body treating compositions
Nonspecific immunoeffector, per se ; or nonspecific...
Synthetic or structurally-modified peptidoglycan or...
542416, 435118, C07D31300, A61K 31365
Patent
active
043905463
ABSTRACT:
There is disclosed a macrolide isolated from the fermentation broth of a microorganism identified as MA-5285 which morphological analysis reveals to be a strain of Streptomyces hygroscopicus. The compound's structure is presented based upon analytical studies. The compound has insecticidal and antiparasitic activity.
REFERENCES:
Derwent Abstract 3189-Abstracting British Patent 850,325.
Chemical Abstracts, 56 14091d (1962).
Gottlieb-"Flavensomycin" appearing in Antibiotics I, pp. 617-620 (1967).
Canonica et al., (I) Tetrahedron Letters 16, pp.537-543 (1961).
Canonica et al., (II) Tetrahedron Letters 26, pp. 3031-3034 (1966).
Box et al., Applied Microbiology 26, pp. 699-704 (1973).
Grove et al. Journal of the Chemical Society, Perkin I, pp. 2441-2443 (1967).
Goetz Michael A.
McCormick Pamela A.
Monaghan Richard L.
Fan Jane T.
Merck & Co. , Inc.
Monaco Mario A.
Rose David L.
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