Antiparasitic macrolide antiobiotics

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549264, A61K 3135, C07D49322

Patent

active

055103723

ABSTRACT:
The present invention relates to certain antibiotic compounds, designated N787-182 compounds herein and derivatives thereof, which are antiparasitic agents, active against insect pest, acari, free-living nematodes and endo- and ectoparasites. This invention also relates to pharmaceutical and other compositions comprising such compounds, methods of using such compounds, the microorganism Streptomyces hygroscopicus ATCC 53718 and mutants or genetically transformed or recombinant form thereof, and processes for producing such compounds.

REFERENCES:
patent: 3950360 (1976-04-01), Aoki et al.
patent: 4200581 (1980-04-01), Fisher et al.
patent: 4423209 (1983-12-01), Mrozik
patent: 4806527 (1989-02-01), Christensen et al.
patent: 5045457 (1991-09-01), Banks et al.

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