Antiparasitic agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

Reexamination Certificate

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C558S303000

Reexamination Certificate

active

07608604

ABSTRACT:
The present invention relates to compounds of the formula (I)or a tautomer or prodrug thereof, or a pharmaceutically acceptable salt of said compound, tautomer or prodrug, wherein:R1, R2, R3, R4and R5are each independently selected from H, halo, CN, CF3and CONH2; compositions containing such compounds and the uses of such compounds as antiparasitic agents.

REFERENCES:
patent: 0 953 565 (1999-03-01), None
patent: 02/49641 (2002-06-01), None
patent: 02/50052 (2002-06-01), None
patent: 02/060257 (2002-08-01), None
patent: 2005/044784 (2005-05-01), None
patent: 2005/121075 (2005-12-01), None
patent: 2006/043654 (2006-04-01), None
patent: 2006/134466 (2006-12-01), None
Stella, Valentino J, Expert Opinion of Therapeutic Patents, Prodrugs as therapeutics, 2004 14(3): 277-280.
Wolff et al. (Burger's Medicinal Chemistry, 5th Ed., vol. 1, pp. 975-977, 1994).
Testa, Bernard, Biochemical Pharmacology, Prodrug Research: futile or fertile? 68 (2004) 2097-2106.
Ettmayer, Peter, Medicinal Chemistry, Lessons Learned from Marketed and Investigational Prodrugs, 47(10) (2004) 2394-2404.
“Tautomer.” Retrieved via the Internet [Dec. 11, 2008], URL: http://en.wikipedia.org/wiki/Tautomer.
Berkowitz, David B. Use of fluorinated functionality in enzyme inhibitor development: Mechanistic and analytical advantages. Journal of Fluorine Chemistry 129 (2008) 731-742.
Patani, George A. Bioisosterism: A rational Approach in Drug Design. Chem. Rev. 96 (1996) 3147-3176.
PCT International Search Report, PCT/IB2008/000250.
Welch and Lim, “The synthesis and biological activity of pentafluorosulfanyl analogs of fluoxetine, fenfluramine, and norfenfluramine”, Bioorganic & Medicinal Chemistry, 15:6659-6666, 2007.

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